[The efficacy of strontium ranelate (Osseor) on fractures in osteoporosis].
نویسنده
چکیده
The clinical experiences with strontium ranelate (Osseor) in osteoporosis treatment are presented. Strontium ranelate (Osseor) has proven efficacy at the vertebral and nonvertebral levels including patients with osteopenia and osteoporosis regardless of patients age.
منابع مشابه
Strontium ranelate in postmenopausal osteoporosis treatment: a critical appraisal
Osteoporosis is a progressive and debilitating disease characterized by a massive bone loss with a deterioration of bone tissues, and a propensity for a fragility fracture. Strontium ranelate is the first antiosteoporotic treatment that has dual mode of action and simultaneously increases bone formation, while decreasing bone resorption, thus rebalancing bone turnover formation. Strontium ranel...
متن کاملStrontium ranelate reduces the risk of vertebral fracture in young postmenopausal women with severe osteoporosis
OBJECTIVES Early osteoporotic fractures have a great impact on disease progression, the first fracture being a major risk factor for further fractures. Strontium ranelate efficacy against vertebral fractures is presently assessed in a subset of women aged 50-65 years. METHODS The Spinal Osteoporosis Therapeutic Intervention (SOTI) was an international, double blind, placebo controlled trial, ...
متن کاملStrontium ranelate: short- and long-term benefits for post-menopausal women with osteoporosis
Strontium ranelate is a bone-seeking element that has been assessed in post-menopausal osteoporosis in two large double-blind, placebo-controlled studies. This treatment is able to decrease the risk of vertebral fractures, by 41% over 3 yrs, and by 49% within the first year of treatment. This risk of non-vertebral fractures is decreased by 16% and, in patients at high risk for such a fracture, ...
متن کاملEffects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial.
OBJECTIVE This study was undertaken to assess the effect of strontium ranelate on nonvertebral and vertebral fractures in postmenopausal women with osteoporosis in a 5-year, double-blind, placebo-controlled trial. METHODS A total of 5,091 postmenopausal women with osteoporosis were randomized to receive either strontium ranelate at 2 gm/day or placebo for 5 years. The main efficacy criterion ...
متن کاملStrontium ranelate reduces the risk of vertebral fractures in patients with osteopenia.
UNLABELLED Many fractures occur in women with moderate fracture risk caused by osteopenia. Strontium ranelate was studied in 1431 postmenopausal women with osteopenia. Vertebral fracture risk reduction of 41-59% was shown depending on the site and fracture status at baseline. This is the first report of antivertebral fracture efficacy in women with vertebral osteopenia. INTRODUCTION Women wit...
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ورودعنوان ژورنال:
- Reumatizam
دوره 55 2 شماره
صفحات -
تاریخ انتشار 2008